Postdoc position in theoretical/computational biophysics
The Statistical Physics of Living Systems and Nano-Biotechnology research group (http://dirac.cnrs-orleans.fr/~piazza/PB/) at the Center for Molecular biophysics (CBM) in Orléans, France, is seeking to fill a postdoctoral position for three years.
The successful candidate will join the group to work on a large-scale project in collaboration with the Servier research laboratory in the Centre region and the University of Tours, aimed at designing in-silico bi-specific antibodies and other complex multi-domain chimeric molecules to be developed as novel agents in immunotherapeutic strategies against cancer and viral pathologies. He/she will work in close collaborations with theoreticians and experimentalists engaged in an ambitious project combining computational design, mathematical modeling, chemical synthesis, biophysical characterization and in-vivo tests of novel immunotherapy multi-domain agents.
More specifically, we will be using LAMMPS  to simulate the dynamics of multi-domain, multi-valent molecules (bi-specific antibodies and more complex molecules) and their binding kinetics with prescribed configurations of receptors, developing on works such as reported in Ref. .
The successful candidate has a keen interest in computational molecular biophysics and has used LAMMPS or similar molecular dynamics packages to simulate complex biomolecular systems. He/she possesses skills in computational physical chemistry, statistical physics and computational physics and holds a Ph.D. degree in any of these or a closely related field.
Interested candidates should send a full CV, cover letter and contact details of three references as a single PDF file to Prof. Francesco PIAZZA, [email protected]…6834… . Applications will be considered until the position has ben filled.
 C. De Michele, P. De Los Rios, G. Foffi and F. Piazza, Simulation and Theory of Antibody Binding to Crowded Antigen-Covered Surfaces, Plos Comp. Biol. - 12(3), e1004752-- (2016)