applying force to mass center of water moleculwe

hi dear usesr.thank you for helping. i supposed to simulate in lammps,water flow with 1058 water molecules in nanochannell at 300K .(piseuille flow)
excuse do you know how can i apply a force to center of mass of every eater molecule in lammps ? or if i apply force to Oxygen in each molecule,instead of mass center of water molecules, in your view thie way what percent error it can produce?tnx