Results difference in NVE+langevin thermostate with NVT

Hi
I have started a project where two fluids are superimposed on a solid surface.
in NVT run, system (in z direction ) will be irregular but in NVE+langevin, The system will be more orderly in z direction. Will there be a difference between these two runs in terms of the final result?
Can I use NVE+langevine instead of NVT?

Langevin and Nose-Hoover are two very different thermostats, so yes the results can be different.